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Mother and Child Health Program (MCH)

Multicentre study program on “Effect of maternal health on pregnancy outcome & glucose homeostasis of the offspring”

Main objectives:

  • To explore the impact of fetal under nutrition on the indications of cardio metabolic disease risk at various stages of infancy.

Specific objectives:

  • To estimate rates of potential exposure to fetal malnutrition.
  • To estimate any association between fetal malnutrition and risk status at birth.
  • To assess differences in the risk status of children exposed to fetal malnutrition as indicated by their birth weight.
  • To assess the beta cell mass and pancreatic function in LBW and NBW children at birth and one year of age.

Moreover, this research program will gather the distinctive prospective study from early pregnancy & explore potential hazards to women with low socioeconomic status. This study will help to address both important public health problems and mechanism of disease.

Research Partner :

  • Diabetic Association of Bangladesh
  • University of Oslo
  • Mother & Child Health Training Institute, Azimpur, Dhaka

Funding Authority - European Union (FP7-HEALTH-2011) and University of Oslo Length of study program- 3 year

Status of the project :

  • Phase I – completed ( 23rd April 2011 to 20th May 2012)
  • Phase II – will begin in February 2013

Overview of Phase I :

  • Total subjects in Visit 1 – 530 ( Normal Pg - 386 + Pg women with glucose intolerance – 110 + Others – 34)
  • Visit 2 (between 24th to 28th week) – 327 ( Normal Pg – 300 + GDM – 27)
  • Delivery (cord sample collection) – 150
  • Provided free services including investigations, consultation and delivery
  • Investigations:
    --   Investigations related to pregnancy screening : Hb%, Urine RME, HbsAg, VDRL, Blood grouping and Rh factor, USG
    --   Investigations related to project outcomes: FBG, 2hAG, HbA1c, Insulin (fasting & after 2hAG), Fasting lipids, S. leptin, S. Renin, S. folate, Homocystine, Ferritin, Vit-D, Vit B12. Blood and placental tissues have been stored for further genetic and epigenetic evaluation

Activities :

  • TOT program – 5
  • Community awareness program – 5
  • Development of software for web based data entry
  • Development of software for nutritional data analysis
  • Development of poster - 4
  • Leaflet distribution – 4000
  • Kick-off Meeting of GIFTS Project took place on 17-18 June 2012 at the Cumberland Lodge, Windsor, UK.

 

Manpower in Phase 1 :

Institute Doctors Nurse Nutritionists Scientific Officer (Lab) Lab Assistant Administrative Officer MLSS Field Officer
BIRDEM
5
0
3
2
2
4
2
2
Azimpur Hospital
12
5
1
2
3
1
4
30
Total
17
5
4
3
5
5
6
32